Skip to main content
Fig. 6 | Molecular Cancer

Fig. 6

From: Characterization of a novel HDAC/RXR/HtrA1 signaling axis as a novel target to overcome cisplatin resistance in human non-small cell lung cancer

Fig. 6

DW22 significantly decreases cisplatin resistance in NSCLC cells in vivo by rescuing HtrA1. a-c The effect of cisplatin, DW22 and cisplatin + DW22 on a relative tumor volume, b tumor weight and c body weight in Balb/c-nu mice xenografted with NCI-H460/CDDP cells. d TUNEL staining of NCI-H460/CDDP xenografted tumors. e Western blot analysis of H4, Ac-H4 and HtrA1 expression in NCI-H460/CDDP xenograft tumors from Balb/c-nu mice. *P < 0.05, **P < 0.01, ***P < 0.001, as compared to the the control group

Back to article page

Molecular Cancer

ISSN: 1476-4598