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Fig. 1 | Molecular Cancer

Fig. 1

From: Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing

Fig. 1

Diverse cell types in PCa were identified by single-cell sequencing. a Workflow of primary PCa samples for scRNA-seq was summarized. Cancerous tissue dissected from radical PCa surgery was cut into small pieces and further digested to single-cell suspension. After cDNA library construction with collected single cells, sequencing and analysis were performed using the 10 × platform. b The main cell clusters in PCa tissue demonstrated by the Uniform Manifold Approximation and Projection (UMAP) plot were colored and labeled according to their featured gene expression profiles. Cell numbers and percentages of each main cluster were counted in the right panel. c A heatmap was generated based on the expression levels of top 50 specific marker genes in each cluster

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Molecular Cancer

ISSN: 1476-4598