Skip to main content
Fig. 8 | Molecular Cancer

Fig. 8

From: RETRACTED ARTICLE: Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation

Fig. 8

Knockdown of AFAP1-AS1 reversed trastuzumab resistance in vivo. a Representative images of the xenograft after intraperitoneal injection with once every 2 days 3 mg/kg trastuzumab treatment for 3 weeks in sh-NC or sh-AFAP1-AS1 cell groups. b Tumor sizes were calculated after injection every 2 days, ***P < 0.001 compared to sh-NC group. c Immunohistochemistry analysis revealed that the tumors developed from sh-AFAP1-AS1 cells displayed lower HER-2 staining than the sh-NC group. d-e Luciferase flux count (d) along with the visible number of metastases in lung (e) were significantly less in sh-AFAP1-AS1 group compared to sh-NC group. f Visualization of the HE-stained lung tissues from different sections

Back to article page

Molecular Cancer

ISSN: 1476-4598