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Table 2 Univariate and multivariate analysis of clinicopathologic factors for RFS of CRC patients in our cohort

From: METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

 

Univariate analysis

Multivariate analysis

Variables

Hazard ratio

P value

95%CI

HR

P value

95%CI

Age (≤60 vs > 60)

1.71

0.309

0.61–4.76

   

Gender

0.875

0.760

0.37–2.06

   

Location

 Ascending colon

1.40

0.574

0.43–4.48

   

 Transverse colon

2.38

0.156

0.72–7.90

   

 Descending colon

0.82

0.856

0.90–7.10

   

 Sigmoid colon and Rectum

1.00

0.490

..

   

Tumor size (≤5 cm vs > 5 cm)

2.33

0.128

0.78–6.91

   

Stage (I + II vs III+ IV)

2.16

0.176

0.71–6.55

   

Local invasion (T1 + T2 vs T3 + T4)

0.525

0.140

0.22–1.23

   

Lymphatic invasion (N0 vs N1 + N2)

2.16

0.176

0.71–6.55

   

Remote metastasis (M0 vs M1)

6.35

0.001

2.13–18.91

7.02

0.008

1.65–29.87

METTL14 level (low vs high)

6.26

0.014

1.44–27.18

21.02

0.011

2.04–216.78