| Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Variables | Hazard ratio | P value | 95%CI | HR | P value | 95%CI |
Age (≤60 vs > 60) | 1.71 | 0.309 | 0.61–4.76 |  |  |  |
Gender | 0.875 | 0.760 | 0.37–2.06 |  |  |  |
Location | ||||||
 Ascending colon | 1.40 | 0.574 | 0.43–4.48 |  |  |  |
 Transverse colon | 2.38 | 0.156 | 0.72–7.90 |  |  |  |
 Descending colon | 0.82 | 0.856 | 0.90–7.10 |  |  |  |
 Sigmoid colon and Rectum | 1.00 | 0.490 | .. |  |  |  |
Tumor size (≤5 cm vs > 5 cm) | 2.33 | 0.128 | 0.78–6.91 |  |  |  |
Stage (I + II vs III+ IV) | 2.16 | 0.176 | 0.71–6.55 |  |  |  |
Local invasion (T1 + T2 vs T3 + T4) | 0.525 | 0.140 | 0.22–1.23 |  |  |  |
Lymphatic invasion (N0 vs N1 + N2) | 2.16 | 0.176 | 0.71–6.55 |  |  |  |
Remote metastasis (M0 vs M1) | 6.35 | 0.001 | 2.13–18.91 | 7.02 | 0.008 | 1.65–29.87 |
METTL14 level (low vs high) | 6.26 | 0.014 | 1.44–27.18 | 21.02 | 0.011 | 2.04–216.78 |