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Fig. 4 | Molecular Cancer

Fig. 4

From: Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer

Fig. 4

Biological characteristics of CRC associated with the WM_Score. a-b WM_Score differences among CMS subtypes of CRC in four GEO-CRC datasets (a) and the TCGA-COAD/READ cohort (b). c-d Heatmap shows the differences in enrichment in the characteristic signaling pathways of CMS subtypes between WM_Score-high and -low groups in four GEO-CRC datasets (c) and the TCGA-COAD/READ cohort (d). Red, high enrichment score; blue, low enrichment score. e WM_Score differences among TNM stages of CRC in eight GEO-CRC datasets. f Differences in the WM_Score between metastasis (red) and non-metastasis (blue) group in the GSE39582 cohort. Wilcoxon test was used to assess the difference. The boxes indicate the median ± 1 quartile, with the whiskers extending from the hinge to the smallest or largest value within 1.5× IQR from the box boundaries

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Molecular Cancer

ISSN: 1476-4598