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Fig. 7 | Molecular Cancer

Fig. 7

From: CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma

Fig. 7

CHEK1 promotes MM growth in vivo and is a potential therapeutic target. A Photographic images of xenograft-bearing mice from each group were taken at day 28. B Time course of tumor growth in NOD-SCID mice treated with vehicle, BTZ, or ADR. C Photographic images of xenografts from NOD-SCID mice of the specified groups on day 28. D Mean tumor weights in the six experimental groups at day 28 after implantation of the specified MM cells. E Photographic images of xenograft-bearing mice from the KD and KD + DOX groups were collected at day 28. F Time course of tumor growth in the NOD-SCID mice of the specified groups. G Xenografts from the NOD-SCID mice of the specified groups were collected at day 28. H Mean tumor weights in the specified two experimental groups at day 28 after implantation of MM cells

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Molecular Cancer

ISSN: 1476-4598