Fig. 1
From: Small extrachromosomal circular DNA (eccDNA): major functions in evolution and cancer
Origins and types of eccDNA. A EccDNA is enriched in specific areas (hotspots), including untranslated (3’-UTR and 5’-UTR) areas, regions with a high GC content, and transcriptionally active chromatin. B EccDNA types based on the genetic content [34]