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Fig. 5 | Molecular Cancer

Fig. 5

From: Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer

Fig. 5

Applications of CRISPR/Cas9-based gene editing tools for basic research of cancer. a CRISPR/Cas9-mediated knockout or knockin was applied to identify and verify of functional gene, including oncogene, tumor-suppressor gene, chemoresistant gene, metabolism-related gene, and cancer stem cell-related gene. b CRISPR/Cas9 library screen for drug target and functional gene. c Application of the CRISPR/Cas13 system for RNA targeting. d In vivo biotinylated dCas9 protein was used for interaction research, and dCas9 protein fused with fluorescent markers such as GFP was used for imaging analysis

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