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Fig. 7 | Molecular Cancer

Fig. 7

From: Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer

Fig. 7

Applications of CRISPR/Cas9 gene editing tools for diagnosis and therapy of cancer. a Using CRISPR/Cas9-based diagnostic system SHERLOCK and DETECTR for detecting cancer. b CRISPR/Cas9 edits immune cells in vitro, and then these cells were administrated to patients to combat against cancer. c Knockout of inhibitory receptors PD-1 by CRISPR/Cas9 technology improves the efficacy of cancer immunotherapy. d Viral genome-specific Cas9-sgRNA eliminates oncogenic virus. e Establishing in vivo tumor model with multiple gene mutations with CRISPR/Cas9 gene editing tools

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