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Table 1 CircRNAs in acute myeloid leukemia. ↑ Indicate increased expression, ↓ Indicate decreased expression. BM (Bone marrow). Ref. (References)

From: Circular RNAs in acute myeloid leukemia

CircRNA
Circ based ID
(Common Name)
Host gene Sample (Expression pattern) Method Target miRNA/Target gene Function Ref.
Circ-VIM Vimentin BM (↑) qRT-PCR   Diagnostic/prognostic biomarker [32]
Circ-FOXO3 FOXO3 BM (↓) qRT-PCR   Diagnostic biomarker [33]
Hsa_circ_0004277 WDR37 BM (↓) Microarray/qRT-PCR   Diagnostic marker, dynamic marker with disease status [34]
Circ_0009910 MFN2 BM (↑) Microarray/qRT-PCR miR-20a-5p Prognostic marker [35]
Hsa_circ_101141 (Circ-ANAPC7) ANAPC7 BM (↑) Microarray/qRT-PCR    [36]
Hsa_circ_104700/Hsa_circ_0005273
(Circ-PTK2)
  BM (↑) qRT/PCR miR-330-5p/FOXM1 Prognostic marker [37]
Hsa_circ_0100181 (CircPAN3) PAN3 BM (↑) Microarray/qRT-PCR miR-153-5p, miR-183-5p/XIAP Chemoresistance [57, 58]
Hsa_circ_0035559 (Circ-ANXA2) ANXA2 BM (↑) Microarray/qRT-PCR miR-23a-5p and miR-503-3p Prognostic biomarker/ Chemoresistance [59]
Hsa_circ_0000488 (Cir-DLEU2) DLEU2 BM (↑) Microarray miR-496/PRKACB Cell proliferation and inhibition of apoptosis [41]
Circ_0000370 FLI-1 Blood (↑) Microarray miR-1299/S100A7A Oncogene [44]
Hsa_circ_0006332 (CircMYBL2) MYBL2 (↑)   FLT3 translation regulation through PTPB1 Oncogene
Therapeutic potential
[45]
Hsa_circ_0075001 NPM1 BM (↑) Microarray   Downregulation of Toll-like receptor signaling [54]
Hsa_circ_0004136   BM (↑) Microarray/qRT-PCR miR-142 and miR-29a Cell proliferation [48]
Hsa_circ_0001346 (circRNF13) RNF13 Blood (↑) qRTPCR miR-1224-5p Cell proliferation and migration [49]
Hsa_circ_0121582 GSK3beta BM (↓) High-throughput sequencing/qRTPCR miR-224/GSK3beta Inhibition of proliferation in AML cells [50]
Hsa_circ_100,290 SLC30A7 BM (↑) qRTPCR Mir-203/Rab10 Regulation of proliferation and apoptosis [51]
Hsa_circ_0079480 ISPD BM (↑) qRT-PCR miR-655-3p/HDGF Regulation of proliferation and apoptosis [53]
Hsa_circ_0002483   BM (↑) qRT-PCR miR-758-3p/MYC Regulation of proliferation, cell-cycle progression, and apoptosis [52]