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Fig. 1 | Molecular Cancer

Fig. 1

From: Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

Fig. 1

CircUSP7 is upregulated in NSCLC tissues. a Heatmap showing USP7 gene-derived circRNAs in NSCLC tissues compared with those in matched adjacent nontumour tissues, as analysed by qRT-PCR. b Diagram of the structure of circUSP7. c Differential expression of circUSP7 in the NSCLC tissues and adjacent nontumour tissues of 126 patients. d A total of 126 patients were divided into the ≤3 cm and >  3 cm size groups. The circUSP7 expression in each group is shown in the diagram. e A total of 126 NSCLC patients were divided into groups negative for lymph node metastasis or positive for lymph node metastasis. The diagram shows circUSP7 expression in each group. f and g Kaplan-Meier analysis of the OS and recurrence of 126 patients with NSCLC according to circUSP7 expression (log-rank test). The data are presented as the mean ± SD of three independent experiments. **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598