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Fig. 6 | Molecular Cancer

Fig. 6

From: Integrative analysis of CRISPR screening data uncovers new opportunities for optimizing cancer immunotherapy

Fig. 6

Identification of potential immunomodulatory agents for potentiating the efficacy of immunotherapies. A Bipartite network showing the interactions between sensitizer/resistor genes and OGs/TSGs. Node size is proportional to the interaction degree; a node with larger size represents that it has more interactions with other nodes. B The proportion of interactions with OGs and TSGs in sensitizers and resistors. Statistical significance was determined using Fisher’s exact tests. C Computational workflow of the inference of potential immunomodulatory agents using the signature matching approach. D Result of drug prediction. The top 10 drugs were labeled in the plot

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Molecular Cancer

ISSN: 1476-4598