Fig. 2
From: Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing
Representative mutational spectra and signature contributions to CPs. (a) The relative proportion of six different possible base-pair substitutions in each sample, (b) the proportion of 96 different trinucleotide substitutions of all SNVs identified in 26 CPs, (c) five signatures’ contribution for each patient in our study cohort. (d) Correlation between content of signature 1 and age at diagnosis of each patient (17 CPs with 0 < signature 1 content < 20%), Pearson’s correlation test was performed