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Fig. 3 | Molecular Cancer

Fig. 3

From: A microRNA-based liquid biopsy signature for the early detection of esophageal squamous cell carcinoma: a retrospective, prospective and multicenter study

Fig. 3

Establishment, validation, and diagnostic performance evaluation of an 8-miRNA signature. ROC curves were used to demonstrate the robust diagnostic value of the 8-miRNA signature in (A) the serum training cohort (AUC = 0.83), (B) the validation cohort 1 (AUC = 0.80), (C) stage I–IV patient samples of validation cohort 2 (AUC = 0.89), and (D) only stage I samples of validation cohort 2 (AUC = 0.82). CI was calculated by 2000 stratified bootstrap replicates

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