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Fig. 2 | Molecular Cancer

Fig. 2

From: METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis

Fig. 2

Knockdown of METTL14 promoted proliferation and invasion of GC. A RT-qPCR and Western blot analysis of the mRNA and protein expression levels of METTL14 in GSE1 and GC cell lines. B RT-qPCR and Western blot analysis of the transfection efficiency of si-METTL14 in MGC-803 and AGS cells or METTL14 in SGC-7901 cells. C MTT analysis of the effects of METTL14 knockdown or overexpression on the GC cell viability. D Colony formation analysis of the effects of METTL14 knockdown or overexpression on the colony formation ability. E Transwell analysis of the effects of METTL14 knockdown or overexpression on the GC cell invasion. Data are the means ± SEM of three experiments. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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Molecular Cancer

ISSN: 1476-4598