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Fig. 3 | Molecular Cancer

Fig. 3

From: Circ-ZEB1 promotes PIK3CA expression by silencing miR-199a-3p and affects the proliferation and apoptosis of hepatocellular carcinoma

Fig. 3

Circ-ZEB1 downregulation reduces the proliferation ability of HCC cells in vitro. A The MTT assay was used to detect the changes in the MHCC-97H activity after the downregulation of circ-ZEB1. B The MTT assay was used to detect the changes in the HCC-LM3 activity after the downregulation of circ-ZEB1. C EdU assay reveals the changes in MHCC-97H cell proliferation after downregulation of circ-ZEB1. D EdU assay reveals the changes in the proliferation of HCC-LM3 cells after the downregulation of circ-ZEB1. E Plate cloning experiment was used to detect cell proliferation changes after transfection of cells with Sh-circ-ZEB1. *P < 0.05 compared with the Sh-NC group. All values are presented as mean ± standard deviation (SD). Comparisons between the groups were analyzed by unpaired t-test, whereas repeated measures analysis of variance (ANOVA) was used to compare several groups. This experiment was performed thrice

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Molecular Cancer

ISSN: 1476-4598