Skip to main content
Fig. 1 | Molecular Cancer

Fig. 1

From: The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway

Fig. 1

CircRNA expression profiling revealed that circALG1 is highly expressed in CRC. A Human circRNA microarray detection of circRNA expression in 3 pairs of cancer and paracancerous tissues from patients with CRC. B Human circRNA microarray detection of circRNA expression in 3 pairs of peripheral blood samples from normal individuals and patients with CRC. C Venn diagram of highly expressed circRNAs in both CRC tissues and peripheral blood. D Expression level of circALG1 in the GSE126094 dataset of the GEO. E qRT-PCR detection of the circALG1 expression levels in 40 pairs of CRC tumours and adjacent tissues. F qRT-PCR detection of the circALG1 expression levels in the peripheral blood of patients with CRC and normal individuals. G qRT-PCR detection of the circALG1 expression levels in the peripheral blood of patients with CRC before and 1 week after surgery. H-J ROC curves illustrating the discriminative capacity of circALG1 to distinguish between tumours and adjacent tissues from patients with CRC (H), between the peripheral blood of patients with CRC and that from healthy individuals (I), and between preoperative and postoperative peripheral blood samples from patients with CRC (J). The results are presented as the mean ± s.d. and are representative of at least 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, #p > 0.05

Back to article page

Molecular Cancer

ISSN: 1476-4598