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Fig. 5 | Molecular Cancer

Fig. 5

From: Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer

Fig. 5

Detailed analysis of the TME stromal cell compartment. A Heatmap analysis of the expression of the PAM50 signature in epithelial cells. B Heatmap analysis of the expression of a curated list of previously published fibroblast and stromal cell markers and other highly upregulated genes. C Volcano plot of differential analysis of macrophages with an M1 vs M2 signature. Canonical M2 marker genes are indicated

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