Molecular Cancer

Table 1 Correlation between clinicopathological features of PDAC and expression of circSTX6, miR-449b-5p (n = 97)

From: CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

Characteristics	circSTX6 expression			miR-449b-5p expression
Characteristics	Low expression (n = 49)	High expression (n = 48)	P value	Low expression (n = 49)	High expression (n = 48)	P value
Gender			0.941			0.617
Male	32	31		33	30
Female	17	17		16	18
Age(years)			0.667			0.162
< 60	12	10		14	8
≥ 60	37	38		35	40
Location			0.437			0.437
Head	30	33		30	33
Body + tail	19	15		19	15
Tumor differentiation			0.008**			0.584
G1 + G2	25	12		20	17
G3	24	36		29	31
TNM stage			0.264			0.019*
I + II	22	27		19	30
III + IV	27	21		30	18
T stage			0.352			0.01*
T1 + T2	25	29		21	33
T3 + T4	24	19		28	15
N stage			0.019*			0.752
N0	28	16		23	21
N1 + N2	21	32		26	27
Nerve invasion			0.102			0.765
No	8	2		6	4
Yes	41	46		43	44
Major vascular invasion			0.612			0.068
No	14	16		11	19
Yes	35	32		38	29
Serum CA19-9(U/ml)			0.424			0.812
< 37	9	6		8	7
≥ 37	40	42		41	41

*P < 0.05, **P < 0.01, ***P < 0.001. G1 stands for well differentiation, G2 stands for moderately differentiation, G3 stands for poor differentiation

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