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Table 1 Correlation between clinicopathological features of PDAC and expression of circSTX6, miR-449b-5p (n = 97)

From: CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

Characteristics circSTX6 expression   miR-449b-5p expression  
Low expression (n = 49) High expression (n = 48) P value Low expression (n = 49) High expression (n = 48) P value
Gender    0.941    0.617
   Male 32 31   33 30  
   Female 17 17   16 18  
Age(years)    0.667    0.162
   < 60 12 10   14 8  
   ≥ 60 37 38   35 40  
Location    0.437    0.437
   Head 30 33   30 33  
   Body + tail 19 15   19 15  
Tumor differentiation    0.008**    0.584
   G1 + G2 25 12   20 17  
   G3 24 36   29 31  
TNM stage    0.264    0.019*
   I + II 22 27   19 30  
   III + IV 27 21   30 18  
T stage    0.352    0.01*
   T1 + T2 25 29   21 33  
   T3 + T4 24 19   28 15  
N stage    0.019*    0.752
   N0 28 16   23 21  
   N1 + N2 21 32   26 27  
Nerve invasion    0.102    0.765
   No 8 2   6 4  
   Yes 41 46   43 44  
Major vascular invasion    0.612    0.068
   No 14 16   11 19  
   Yes 35 32   38 29  
Serum CA19-9(U/ml)    0.424    0.812
   < 37 9 6   8 7  
   ≥ 37 40 42   41 41  
  1. *P < 0.05, **P < 0.01, ***P < 0.001. G1 stands for well differentiation, G2 stands for moderately differentiation, G3 stands for poor differentiation