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Fig. 3 | Molecular Cancer

Fig. 3

From: CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma

Fig. 3

CircGPR137B inhibits in vitro cell growth. A RT-qPCR analysis of the expression levels of circGPR137B in different HCC cell lines. B RT-qPCR analysis of the overexpression efficiency of circGPR137B lentiviruses in HepG2 and Hep3B cell lines and the knockdown efficiency of sh-circGPR137B lentiviruses in SK-hep-1 cells. C MTT. Colony formation (D) and Transwell analysis (E) of the effects of circGPR137B overexpression or knockdown on cell proliferation, colony formation and cell invasion in HCC cell lines. Data are the means ± SEM of three experiments. *P < 0.05; **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598