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Fig. 4 | Molecular Cancer

Fig. 4

From: CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma

Fig. 4

CircGPR137B has a negative correlation with miR-4739 in HCC. A, B Identification of the binding sites between circGPR137B and 5 miRNAs. C. Luciferase activity of circGPR137B 3’UTR was evaluated in HCC cells exposed to the treatment of 5 miRNA mimics. D, E FISH analysis of the expression levels of miR-4739 in 87 pairs of HCC tissue samples. F Pearson correlation analysis of the correlation of circGPR137B with miR-4739 in HCC. G TCGA analysis of the expression levels of miR-4739 in 220 HCC tissue samples. H Kaplan–Meier analysis of the association of miR-4739 high or low expression with overall survival in HCC

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Molecular Cancer

ISSN: 1476-4598