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Fig. 3 | Molecular Cancer

Fig. 3

From: A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma

Fig. 3

Receiver operating characteristic curves of three models for skin reaction (A) and dysphagia (B). All models were generated by using multivariable logistic regression. The genetic model only involved genetic factors: rs6711678, rs4848597, rs4848598, and rs2091255 for skin reaction, and rs584547 for dysphagia. During the calculation, rs6711678, rs4848597, rs4848598, and rs2091255 were combined as polygenic risk scores. The clinical model involved clinical factors only, which include age, sex, BMI, smoking status, stage, EBV infection, and radiotherapeutic regimen. The combined model integrated both genetic and clinical factors. BMI: body mass index, EBV: Epstein-Barr virus, AUC: area under curve

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Molecular Cancer

ISSN: 1476-4598