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Fig. 6 | Molecular Cancer

Fig. 6

From: The reversion of DNA methylation-induced miRNA silence via biomimetic nanoparticles-mediated gene delivery for efficient lung adenocarcinoma therapy

Fig. 6

The inhibition of LUAD cell migration, invasion, and endothelial-to-mesenchymal transition. A549 and NCI-H1299 cells were treated with REMAIN or si-ADAM9 for 48 h. The mRNA (A) and protein (B) levels of ADAM9 in A549 and NCI-H1299 cells treatment with REMAIN, respectively. (C) Wound healing assays measured cell migration. (D) Transwell assays measured cell invasion. (E) Western blot assays determined the expression of EMT markers E-cadherin, N-cadherin, and Vimentin. *, P < 0.05; **, P < 0.01; ***, P < 0.001

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