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Fig. 6 | Molecular Cancer

Fig. 6

From: Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma

Fig. 6

The therapeutic effects of chemosynthetic MIAC peptide on RCC in vitro and in vivo. The inhibitory activity of chemosynthetic MIAC peptide on RCC cell proliferation (A) and cell migration (B). Flow cytometry indicated that the MIAC inhibits cell cycle progression of RCC cells (C). Flow cytometry assays showed that the MIAC accelerated the apoptosis of RCC cells (D). E Gross image of subcutaneous tumors with different dosage of MIAC and positive drug (sunitinib/Axitinib). F Tumor growth curve of differnt groups. G Analysis of tumor inhibition rate of MIAC exogenous peptides and positive drugs after administration. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598