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Fig. 7 | Molecular Cancer

Fig. 7

From: Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma

Fig. 7

Schematic diagram of the molecular mechanism of MIAC micropeptide inhibiting RCC cell growth and metastasis. MIAC directly binds to AQP2 and suppresses RCC growth and metastasis through inhibiting PI3K/AKT and MAPK downstreams of EREG/EGFR signalling. MIAC has inhibitory effects on RCC in vitro and in vivo, suggesting its potential application in kidney cancer treatment

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Molecular Cancer

ISSN: 1476-4598