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Fig. 4 | Molecular Cancer

Fig. 4

From: Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition

Fig. 4

Cell types of the tumor microenvironment and their relationship to the immune cycle. Schematic depiction of the major cell types of the tumor microenvironment involved in promoting (green shading) or suppressing (red shading) the anti-tumor response of immune checkpoint inhibitor therapies, and the stages of the immune cycle that these cells impact. The dual shading for TAMs indicates the opposing functions of the two TAM endotypes. CAF, cancer-associated fibroblast; MDSC, myeloid-derived suppressor cell; TAM, tumor associated macrophage; Treg, regulatory T cell

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Molecular Cancer

ISSN: 1476-4598