Fig. 6From: Myeloid-derived suppressor cells: an emerging target for anticancer immunotherapyThe plasticity of MDSCs. MDSCs can induce Tregs and differentiate into TAMs, as well as mature DCs and M2 macrophages. Moreover, MDSCs were found to be derived from CAFs under the influence of IL-6 and turned into fibrocytes in the lung. MDSCs can also differentiate into osteoclasts and have a complex crosstalk with Th17 cellsBack to article page