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Fig. 1 | Molecular Cancer

Fig. 1

From: CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment

Fig. 1

Expression of CREB3L1 in thyroid cancer and its clinical prevalence. A The expression of CREB3 family members in thyroid cancer subtypes and normal tissues was analyzed in four integrated datasets. B The relationship between CREB3L1 expression and tumor stage in thyroid cancer was retrieved from the GEPIA database. C Overall survival (OS) analysis of CREB3L1 in thyroid cancer was retrieved from the Kaplan–Meier plot database. D Progression-free survival analysis of CREB3L1 in an independent thyroid cancer cohort. Immunohistochemistry (IHC) staining of CREB3L1 was conducted in tissue microarrays contained 234 PTC samples. E IHC staining were used to analyze CREB3L1 expression in NT, PTC, and ATC tissues. F CREB3L1 expression in different thyroid cancer cell lines was analyzed by western blotting (WB). Data are presented as the mean ± standard deviation (SD). *P < 0.05, **P < 0.01 versus the respective NT, PTC, or ATC

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Molecular Cancer

ISSN: 1476-4598