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Table 3 Univariate and multivariate Cox regression analysis of CREB3L1 expression with patient prognosis

From: CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

P-value

HR (95% CI)

P-value

Age

1.311e + 09 (0-inf)

0.9968

  

Gender

1.896 (0.686–5.241)

0.2174

  

T staging

2.629 (1.417–4.876)

0.00217*

  

N staging

1.463 (0.4777–4.483)

0.5051

  

M staging

5.443 (1.161–25.52)

0.03159*

  

TNM staging

2.434 (1.542–3.842)

0.0001331*

3.621 (1.388–9.447)

0.00853*

Maximal tumor diameter

1.403 (1.072–1.836)

0.0137*

  

Lymph node number

1.003 (0.9068–1.11)

0.9527

  

Primary neoplasm focus type

0.2495 (0.05635–1.105)

0.06745

  

Iodine radiotherapy

4.005e + 08 (0-inf)

0.9991

  

Lymph node preoperative scan indicator

1.496 (0.4241–5.273)

0.5313

  

History of neoadjuvant treatment

18.24 (3.976–83.66)

0.0001871*

  

CREB3L1 expression

4.831 (1.754–13.3)

0.00231*

4.979 (1.074–23.08)

0.04025*

  1. HR Hazard ratio
  2. * Statistical significance