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Fig. 6 | Molecular Cancer

Fig. 6

From: The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy

Fig. 6

Characterizing Epithelial/Tumor cell subsets within the tumor microenvironment of Esophageal Adenocarcinoma. A UMAP embedding overlaid with cluster cell type annotations and UMAP embeddings split by treatment and tissue type. B UMAP embeddings overlaid with expression of canonical Epithelial cell type markers. C Average expression profile of top cluster marker genes. D Breakdown of cluster proportions by sample, chemotherapy treatment and tissue type. E Comparison of Adjacent Normal (AN) vs Tumor (T), pre vs post chemotherapy and Mandard score cluster proportions. Points represent within-sample cluster proportion of total sample epithelial cells and p values determined by Mann-Whitney test

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Molecular Cancer

ISSN: 1476-4598