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Fig. 2 | Molecular Cancer

Fig. 2

From: Tumor buster - where will the CAR-T cell therapy ‘missile’ go?

Fig. 2

Common CAR-T cell therapy targets in hematological malignancies. B-ALL: B-acute lymphoblastic leukemia; BAFF-R: B-cell activating factor receptor; TSLPR: thymic stromal lymphopoietin receptor; T-ALL: T-acute lymphoblastic leukemia; AML: acute myeloid leukemia; NKG2DL: natural killer group 2 member D ligand; CLL1: C-type lectin like molecule 1; FLT3: FMS-like tyrosine kinase 3; WT1: wilms tumor 1; CLL: chronic lymphocytic leukemia; ROR: receptor tyrosine kinase like orphan receptor; BCMA: B-cell maturation antigen; MM: multiple myeloma; SLAMF7: signaling lymphocytic activation molecule F7; GPRC5D: G protein-coupled receptor class-C group-5 member-D; B-NHL: B-cell non-Hodgkin’s lymphoma; T-NHL: T-cell non-Hodgkin’s lymphoma; TRBC: T cell receptor β-chain constant domains; HL: Hodgkin’s lymphoma

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