Retraction Note to: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis
Molecular Cancer volume 21, Article number: 209 (2022)
Retraction note to: Mol Cancer 17, 98 (2018)
The Editor in Chief has retracted this article. After publication, concerns were raised in regards to some figures, specifically:
· Fig. 4C: in the Hoechst 33342 row, the LV-PVT1 panel of Capan-2 appears to correspond to the sh-PVT1-1+rapa panel of HPAF-II with a rotation and background brightness difference;
· Fig. 4C: there appears to be a partial overlap between HPAF-II panels for sh-NC and sh-PVT1-1 in all three rows;
· The LV-PVT1+3MA plot in Fig. 4E is unexpectedly similar to the miR20a+PVT1 plot in Fig. S4C.
The authors did not provide a sufficient explanation. Additionally, it appears the authors initially obtained only a provisional “fast-track” ethics approval for the study and applied for full approval at revision stage. This is not in line with journal policy.
Therefore, the Editor in Chief has lost confidence in the integrity of the article's findings. Fengting Huang, Wenying Chen, Juanfei Peng, Yuanhua Li, Wanling Yang, Herui Yao and Shineng Zhang agree to this retraction. Yanyan Zhuang, Zhe Zhu and Chunkui Shao did not respond to correspondence from the Editor about this retraction.
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Huang, F., Chen, W., Peng, J. et al. Retraction Note to: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis. Mol Cancer 21, 209 (2022). https://doi.org/10.1186/s12943-022-01678-7