Fig. 1

Schematic illustrations of synthesis of INC280-PFCE NPs and corresponding theranostic strategy and characterization. A Scheme of the synthesis of the INC280-PFCE NPs and theranostic strategy. B Size distribution of INC280-PFCE NPs determined by DLS. C The average zeta potential values of PFCE NPs and INC280-PFCE NPs. D INC280-PFCE NPs were characterized by TEM. Scale bar is 100 nm for small view and 1000 nm for large view. E After storage at 4, 25 and 37 °C, size stability tests of INC280-PFCE NPs over 6 consecutive weeks. F ¹⁹F-MR images of INC280-PFCE NPs with increasing concentrations of ¹⁹F (C_F). 1–5: 2.59, 5.19, 10.37, 20.74, 41.48 mg/mL, respectively. G ¹⁹F-NMR of INC280-PFCE NPs