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Fig. 1 | Molecular Cancer

Fig. 1

From: An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer

Fig. 1

Training of exosomal miRNAs and cell-free miRNAs in predicting lymph node metastasis from high-risk T1 CRC patients. A A receiver operating characteristic (ROC) curve analysis to evaluate the performance of cell-free miRNAs panel. B ROC curve analysis to evaluate the performance of the exosomal miRNAs panel. C Correlation of 4 miRNAs’ expression between exosomal component and total serum. D ROC curve analysis to evaluate the performance of exosomal and cell-free miRNAs combination panel. E Waterfall plot for modified risk score distribution in a training cohort. Cf-: cell-free, exo: exosomal, LNN: lymph node metastasis negative, LNP: lymph node metastasis positive, AUC: area under the curve

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