Fig. 3
From: CAR T cells: engineered immune cells to treat brain cancers and beyond
A glance at CAR T cell-based therapeutic prospect in brain cancer management. CAR T cells recognize some brain tumor-specific antigens that are targeted with an ambition to eliminate brain cancer cells. Some malignant growths in the brain can damage the BBB and help CAR T cells to cross the BBB to reach the tumor site. In addition, some delivery strategies allow delivering CAR T cells to the tumor site enabling the achievement of better therapeutic efficacy in brain tumor management