Fig. 4
From: Targeting Pim kinases in hematological cancers: molecular and clinical review
Microarray Expression of Pim kinases in AML, CML, ALL, CLL, and MDS. A-B Data are compiled from the BloodSpot Data base (https://servers.binf.ku.dk/bloodspot/) using expression data from the Microarray Innovations in Leukemia study (MILE) [11, 75]. Data are derived from four groups of leukemia: AML, CML, ALL, and CLL. The data are derived from 2095 patients, performed in various laboratories across the world. A Jitter strip chart demonstrating expression data of Pim-1, Pim-2, and Pim-3 across various subclasses of AML, CML, ALL, CLL, and MDS. B Hierarchical differentiation trees for the expression of Pim-1, − 2, and − 3 in AML, CML, ALL, CLL, and MDS. Pim kinase expression levels are indicated by the legend, whereby the size and color of the nodes indicates general expression patterns in various classes and subclasses of leukemia