Fig. 2
From: Lung cancer immunotherapy: progress, pitfalls, and promises
Immune interaction between T-cells, APCs, and cancer cells A. Schematic representing the mechanism of antigen-specific T cell activation. DCs play a crucial role in anti-tumor immunity due to their exceptional capacity to activate T cells following the central dogma of three signals. S1: Signal 1; S2: Signal 2; S3: Signal 3; TME: Tumor microenvironment; DC: Dendritic cell. B. Schematic showing immune interaction between T cell and APC; T cell with tumor cells. The T cell co-inhibitory and co-stimulatory molecules are shown in black and red fonts respectively. APC: Antigen presenting cell, L: Ligand