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Fig. 7 | Molecular Cancer

Fig. 7

From: LncRNA-BC069792 suppresses tumor progression by targeting KCNQ4 in breast cancer

Fig. 7

Rescue experiment. a Overexpression of BC069792 inhibits the proliferation of breast cancer cells (P < 0.0001), After simultaneously overexpressing miR-658 mimics (P = 0.0002) and miR-4739 mimics (P < 0.0001), the proliferation of breast cancer cells was enhanced. b Overexpression of BC069792 inhibited the migratory ability of breast cancer cells (P < 0.0001). breast cancer cells have enhanced migratory ability after transfection with miR-658mimics (P = 0.0009) or miR-4739mimics (P < 0.0001). c After overexpression of BC069792 and simultaneous transfection of miR-658 mimics (P = 0.005) or miR-4739 mimics (P = 0.026), the elevated KCNQ4 protein expression level was decreased. d The p-AKT protein level was elevated in rescue experiments. e The negative correlation of KCNQ4 with p-AKT was restored. (:P < 0.05, :P < 0.01, :P < 0.001,.:P < 0.0001, ns: P > 0.05)**********

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