Fig. 2

CircCCAR1 promotes HCC growth in vitro and in vivo. A-B A CCK-8 assay was conducted in HCC cells after circCCAR1 overexpression or depletion. *p < 0.05, **p < 0.01 vs. vector; #p < 0.05, ##p < 0.01 vs. sh-NC. C A colony formation assay was conducted in HCC cells after circCCAR1 overexpression or depletion. *p < 0.05, **p < 0.01 vs. vector; #p < 0.05, ###p < 0.001 vs. sh-NC. D Photograph of xenograft tumors (n = 5). E Growth curves of xenograft tumors. F Tumor weight was determined. G Ki67 staining of xenograft tumors. **p < 0.01, ***p < 0.001 vs. vector; ###p < 0.001 vs. sh-NC