Fig. 6From: A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancerAnalysis of IGF2BP2 targets in tumor and metastatic CRC tissues. A, B Cumulative plot of gene expression (log2 fold change) in primary (A) and metastatic (B) CRC tissues compared to their respective control tissues. Gene subgroups were built according to IGF2BP2 binding determined by IGF2BP2 CLIP data (see Methods) and representing all genes (black), IGF2BP2 positive genes (IGF2BP2+ ,blue) and IGF2BP2 negative genes (IGF2BP2-,green). Numbers in brackets denote the number of genes in each categoryBack to article page