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Fig. 1 | Molecular Cancer

Fig. 1

From: The senescence journey in cancer immunoediting

Fig. 1

Senescence inducers and paracrine effects of SnCs

Overview of senescence inducers and paracrine effects of SnCs on the surrounding microenvironment. The senescence program can be activated by different stress stimuli (shown on the left) such as cytotoxic chemotherapeutic drugs, replicative and oxidative stress. On the other hand, SASP factors produce paracrine effects impinging on cancer onset and progression (shown on the right). SASP can induce senescence of surrounding cells (paracrine senescence), facilitate tissue remodeling and recruitment of immune cells

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Molecular Cancer

ISSN: 1476-4598