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Table 3 Association between C/C genotype in rs822336 and PFS of NSCLC patients treated with anti-PD-1/PD-L1 therapy: multivariate analysis

From: rs822336 binding to C/EBPβ and NFIC modulates induction of PD-L1 expression and predicts anti-PD-1/PD-L1 therapy in advanced NSCLC

Variables

HR

p-value

95% CI

Univariate p-value

rs822336C/C vs. rs822336G/C or G/G

0.5163762

0.005

0.3241144–0.8226861

0.0030

Current smoker vs. never /previous smoker

0.3619732

0.015

0.159869–0.8195749

0.0140

Age

0.9743548

0.254

0.9317971–1.018856

0.0007

ECOG PS 0 vs.

1/2

1.226831

0.288

0.8413328–1.788963

0.0300

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Molecular Cancer

ISSN: 1476-4598