From: Crosstalk between metabolism and cell death in tumorigenesis
Cell death | Medicine | Inhibition or promotion | Target | References | |
---|---|---|---|---|---|
Pyroptosis | NO.0449 − 0145 | Promotion | APE1A | [275] |  |
Pyroptosis | Metformin | Promotion | AMPK/SIRT1/NF-κB | [305] |  |
Pyroptosis | Paclitaxel, Cisplatin, Miltirone, Tetraarsenic hexoxide | Promotion | GSDME | Â | |
Pyroptosis | α-KG | Promotion | DR6 | [137] |  |
Pyroptosis | Val-boroPro | Promotion | CARD8 | [309] | Â |
Pyroptosis | Benzimidazoles | Promotion | NF-κB/NLRP3/GSDMD | [310] |  |
Pyroptosis | Dihydroartemisinin | Promotion | AIM2/Caspase-3/ DFNA5 | [311] | Â |
Pyroptosis | Metformin | Promotion | FOXO3 | [312] | Â |
Pyroptosis | Disulfiram, Cucurbitacin B | Inhibition | GSDMD | Â |