Figure 1

Dose response analysis of Caki^parand Caki^res. (A) Growth efficacy of increasing concentrations of everolimus on Caki^par and Caki^res cell growth from 24 h to 72 h. *Indicates significant difference to controls, set to 100% (SD ≤ 16%, n = 6). IC₅₀-values of Caki^par and Caki^res cells were calculated from dose response analysis. (B) Cell cycle analysis of unsynchronized and synchronized Caki^par and Caki^res cells in subconfluent cell cultures. The cell phase is expressed as percentage of total cells. The figure shows one of five separate experiments.