Figure 4From: HDAC-inhibition counteracts everolimus resistance in renal cell carcinoma in vitro by diminishing cdk2 and cyclin ACell growth analysis. Growth inhibitory efficacy of 1 nM or 1 mM VPA in Cakipar and Cakires cells treated for one (A) or two weeks (B). *Indicates significant difference to untreated controls, set at 100%. #Indicates significant difference between Cakipar + VPA and Cakires + VPA (SD ≤ 22%, n = 6).Back to article page