Table 1 Identified TQ targets belonging to cancer-related pathways
Network | Identified substrate | Phospho site | Prot ID | Folds up (24 h) |
|---|---|---|---|---|
Cytoskeleton | EphB1 | Y594 | NP_004432 | 2.93 |
| Â | Lamin A/C | S22 | CAA27173 | 2.45 |
| Â | MAP2v | S1679 | NP_114034 | 2.30 |
| Â | Syntaxin 1A | S14 | NP_004594 | 2.22 |
| Â | Lamin B1 | S395 | NP_005564 | 2.12 |
| Â | SNAP23 | T24 | NP_003816 | 2.08 |
PI3K/AKT | Lck | S158 | AAH13200 | 3.45 |
| Â | HSP22 | S14 | NP_0055180 | 3.32 |
| Â | PKR | T451 | NP_002750 | 3.92 |
| Â | Beta-2-adrenergic receptor-B2AR | S262 | NP_000015 | 2.80 |
| Â | AKT1 | Y326 | NP_005154 | 2.22 |
| Â | Bone marrow kinase BMX-ETK | Y40 | AAC08966 | 2.16 |
| Â | Glucocorticoid receptor | S211 | NP_000167 | 2.15 |
| Â | PAK1 | T212 | AAC24716 | 2.12 |
| Â | Nitric oxide synthase 1 | S852 | NP_000611 | 2.09 |
| Â | CHOP | S79 | NP_004074 | 2.08 |
| Â | Metabotropic glutamate receptor 1 | T695 | AAA87843 | 2.05 |
| Â | RAF1-c-RAF | S43 | NP_002871 | 2.00 |
Wnt | Beta-catenin | Y142 | NP_001895 | 2.89 |
| Â | T-cell transcription factor 4 | S60 | NP_110383 | 2.59 |
| Â | N-myc | S263 | NP_005369 | 2.43 |
| Â | L1 cell adhesion molecule | S1152 | NP_000416 | 2.25 |
| Â | APC | S2054 | NP_000029 | 2.06 |
| Â | MAP3K7-TAK1 | S192 | NP_663304 | 2.01 |