Table 1 Characteristics 54 patients with oral cancer, and the association of miR-196a and miR-196b expressions with clinicopathological status
| Â | miR-196a | miR-196b | ||
|---|---|---|---|---|
Characteristics ( n ) | low ( n ,%) | high ( n ,%) | low ( n ,%) | high ( n ,%) |
Sex | Â | Â | Â | Â |
  Female (5) | 0 (0) | 5 (100) | 1 (20) | 4 (80) |
  Male (49) | 12 (24) | 37 (76) | 18 (37) | 31 (63) |
  *P value | 0.210 |  | 0.455 |  |
Age | Â | Â | Â | Â |
  ≤ 55 years old (30) | 6 (20) | 24 (80) | 9 (30) | 21 (70) |
  > 55 years old (24) | 6 (25) | 18 (75) | 10 (42) | 14 (58) |
  P value | 0.661 |  | 0.372 |  |
Alcohol drinking | Â | Â | Â | Â |
  No (29) | 6 (21) | 23 (79) | 10 (34) | 19 (66) |
  Yes (25) | 6 (24) | 19 (76) | 9 (36) | 16 (64) |
  P value | 0.770 |  | 0.907 |  |
Cigarette smoking | Â | Â | Â | Â |
  No (24) | 3 (12) | 21 (88) | 7 (29) | 17 (71) |
  Yes (30) | 9 (30) | 21 (70) | 12 (40) | 18 (60) |
  P value | 0.124 |  | 0.407 |  |
Betel quid chewing | Â | Â | Â | Â |
  No (17) | 3 (18) | 14 (82) | 7 (41) | 10 (59) |
  Yes (37) | 9 (24) | 28 (76) | 12 (32) | 25 (68) |
  P value | 0.584 |  | 0.532 |  |
Pathologic T-status | Â | Â | Â | Â |
  T1-T2 (25) | 6 (24) | 19 (76) | 9 (36) | 16 (64) |
  T3-T4 (29) | 6 (21) | 23 (79) | 10 (34) | 19 (66) |
  P value | 0.770 |  | 0.907 |  |
Pathologic N-status | Â | Â | Â | Â |
  pN0 (32) | 12 (37) | 20 (63) | 16 (50) | 16 (50) |
  pN + (22) | 0 (0) | 22 (100) | 3 (14) | 19 (86) |
  *P value | 0.001 |  | 0.006 |  |
Pathologic stage | Â | Â | Â | Â |
  I - II (19) | 6 (32) | 13 (68) | 8 (42) | 11 (58) |
  III - IV (35) | 6 (17) | 29 (83) | 11 (31) | 24 (69) |
  P value | 0.223 |  | 0.433 |  |
Differentiation | Â | Â | Â | Â |
  Well (15) | 5 (33) | 10 (67) | 6 (40) | 9 (60) |
  Moderate (35) | 7 (20) | 28 (80) | 13 (37) | 22 (63) |
  Poor (4) | 0 (0) | 4 (100) | 0 (0) | 4 (100) |
  #P value | 0.137 |  | 0.280 |  |
Total | 12 (22) | 42 (78) | 19 (35) | 35 (65) |