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Figure 5 | Molecular Cancer

Figure 5

From: SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients

Figure 5

SAP-dependent Mkl1 target genes are associated with typical high-proliferative poor outcome classes in breast cancer. The expression levels for the SRF-dependent/SAP-independent (A) and SRF-independent/SAP-dependent (B) gene sets are analyzed across the 1881-sample breast cancer data set stratified according to PAM50 subtypes (left panels), estrogen receptor (ER)-status (middle panels) and histological grade (right panels), and represented by box plots using the GOBO bioinformatics tool. The number of tumors in each breast cancer subtype and the significant difference in gene expression (P-value calculated using ANOVA) between them are shown above the box plots.

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Molecular Cancer

ISSN: 1476-4598