Figure 2
From: Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis
Expression of CK1 isoforms in cancer. (A) Shown are the color-coded RNA expression levels of CK1α, δ, ϵ, γ1, γ2, ϵ3 (CSNK1A1, CSNK1D, CSNK1E, CSNK1G1, CSNK1G2, CSNK1G3) in different tumor types as determined by the CellMiner database for gene expression analysis of 60 cancer cell lines from the NCI60 panel. Z-scores for the six isoforms were calculated and subjected to the Gene-Pattern analysis software for heatmap generation using the Gene-Pattern online tools (http://genepattern.broadinstitute.org/gp/pages/index.jsf). Blue depicts low expression levels and red high expression levels. (B) The Ramaswamy Multi-cancer dataset (public available at http://www.broadinstitute.org/cancer/software/genepattern/datasets/) was used for analysis of the z-scored expression levels in different tumor tissue samples and again used for heatmap illustration.