Figure 2From: Pathway-specific differences between tumor cell lines and normal and tumor tissue cellsA module map showing the direction of regulation of cellular pathways that were identified as significantly altered in cell lines compared to tumor tissue (CL - T) in at least 2 of the 6 tissues considered in this study. In (a), a pathway is deemed significantly altered if at least 80% of the genes in the pathway are shifted in a common direction. In (b), a pathway is deemed significantly altered if at least 70% of the genes in the pathway are shifted in a common direction. The color red indicates an upregulated pathway, the color green indicates a downregulated pathway, and the color black indicates that the pathway was not significant in that comparison.Back to article page